WuXi Biologics is a global Contract Research Development and Manufacturing Organization (CRDMO) that provides open-access, integrated technology platforms for biologics drug development.
WuXi Biologics' roots date back to 2010, and began building out capabilities and facilities required for biologics discovery, development and good manufacturing practices (GMP).
As of 2021, WuXi Biologics has 18 manufacturing sites including ten in China, three in the United States, two in Ireland, two in Germany, and one in Singapore.
In August 2020, WuXi Biologics was selected to become a component of the Hang Seng Index in Hong Kong.
In January 2024, WuXi Biologics' share price fell on news that the United States Congress had introduced legislation to block any federal government contracts with the company due to national security concerns.
Facilities in Asia
Shanghai, China
WuXi Biologics has two sites in Shanghai, one in the Shanghai Waigaoqiao Free Trade Zone and the other in Fengxian.
Wuxi, China
WuXi Biologics has two sites located in
Wuxi City, China. The
Binhu District site contains MFG1, MFG2, MFG4 and MFG5.
and the Wuxi New Area site contains labs dedicated to the antibody drug conjugate development and production.
Hangzhou, China
As of March 2021, WuXi Biologics will have two sites in Hangzhou China.
On March 17, 2021, WuXi Biologics announced an equity agreement with Pfizer China to acquire its newly built $350 million Hangzhou global biotechnology center site and facilities (MFG20).
Suzhou, China
As of March 2021, WuXi Biologics will have two sites located in the city of
Suzhou, China.
On March 18, 2021, WuXi Biologics announced a purchase agreement with CBC Group which will allow it to acquire over a 90% interest in CMAB Biopharma Group. The transaction is expected to close in the second quarter of 2021. Along with the controlling stake, WuXi Biologics will also acquire a 7000L bioreactor capacity manufacturing facility (MFG21) in Suzhou and associated liquid and lyophilization (DP21) fill and finish production lines.
Chengdu, China
Currently slated to open in 2023, the
Chengdu facility (MFG12) will be a , with an integrated manufacturing center for innovative biologics and dedicated to R&D and commercial-scale bulk active pharmaceutical ingredient (API) production with an initial bioreactor capacity of for commercial production and for clinical production.
Shijiazhuang, China
Currently slated to open in 2022, the
Shijiazhuang facility MFG8 will be and dedicated to development and API manufacturing with an initial bioreactor capacity of 48,000 liters.
Singapore
On May 24, 2018, WuXi Biologics announced it will be building a $60 million facility (MFG10) in
Singapore which will feature an initial bioreactor capacity of 4,500 liters made up of two 2,000 liter fed-batch reactors and one 500 liter continuous processing perfusion reactor to open in 2023.
The project is backed by the Singapore Economic Development Board and will be dedicated to clinical and small volume commercial production as well as early-stage bioprocess development.
Facilities in Europe
Leverkusen, Germany Facility
On January 17, 2020, WuXi Biologics and
Bayer announced an acquisition agreement in which WuXi Biologics would take over the operations and lease a fill site in Leverkusen, Germany. Based on the agreement, the site would perform the final fill-finish of various biologics products produced by WuXi's API sites, and act as a backup for filling operations for Bayer's
Kovaltry anti-hemophilic infusions which are primarily finished in another plant in Berkeley, California.
Wuppertal, Germany Facility
On December 21, 2020, WuXi Biologics and Bayer announced a new acquisition agreement for a drug substance (DS) production site for €150 million in
Wuppertal, Germany.
Dundalk, Ireland Site
Active ingredient production facilities
In April 2018,
WuXi Biologics announced plans to build a new biologics drug substance manufacturing facility on in Dundalk, Ireland. The project is directly supported by the Irish Government through
IDA Ireland, with a cost of approximately $394 million. When completed, the facility will be one of the world's largest plants supporting single-use bioreactors and will help accelerate the development of biologic drugs in Europe.
MFG6 will have a perfusion bioreactor capacity of 6,000 liters in a continuous bioprocessing configuration and MFG7 will have a 48,000 liter bioreactor capacity in a traditional fed-batch configuration.
Vaccine production facility
In November 2019, WuXi Vaccines, a subsidiary of WuXi Biologics, announced that it would invest an additional $240 million to build a new vaccine manufacturing facility at the Dundalk, Ireland site. The vaccine site planned includes drug substance manufacturing facilities, drug product manufacturing, Manufacturing Science and Technology Labs as well as Quality Control labs. In February 2020, WuXi Vaccines announced it had signed a 20-year, $3 billion contract with an unidentified "global vaccine leader" to produce one of the unidentified company's vaccine products at the new facility.
Facilities in the United States
Massachusetts
In May 2020, WuXi Biologics announced that it had secured a deal with the Worcester Business Development Corporation at The Reactory, a master-planned manufacturing hub project in Worcester, Massachusetts. The two-story, facility will cost $60 million and will employ 150 when it is completed in 2022. The Worcester City Council granted a 20-year, $11.5 million tax increment financing plan to help seal the deal. The new facility will have 16,000 liters of bioreactor capacity, which will include four 4,000-liter traditional fed-batch units and one 500-liter perfusion-based continuous processing unit and will be named MFG11.
New Jersey
In June 2020, WuXi Biologics announced that it had signed a ten-year lease for a clinical manufacturing facility (MFG18) in Cranbury, NJ. The facility had previously been leased by Outlook Therapeutics and will install a total of of bioreactor capacity, process development, and quality control labs, along with supporting functions.
Pennsylvania
In May 2020, WuXi Biologics announced it had leased a process development lab in King of Prussia, Pennsylvania at Discovery Labs, a former
GlaxoSmithKline manufacturing site.
In 2024, WuXi announced that the site in King of Prussia would cease operations.
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